Prostate Biopsy Prep Instructions

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You have been scheduled for a prostate ultrasound and biopsy. This was scheduled due to an elevated PSA, abnormal rectal exam, or both. To ensure a good quality and safe procedure please do the following:

  • You should stop any prescribed blood thinners (e.g. aspirin, Coumadin, Xarelto, Eliquis, Plavix, etc.) prior to the procedure. The amount of time will depend on the specific medication. Please check with the prescribing doctor before discontinuing this medication, for instructions on when to stop and when to resume these medications.
  • One week (7 days) prior to your biopsy, you should discontinue any anti-inflammatory medication (NSAIDs), such as Motrin, Advil, Aleve, or Naprosyn.
  • You will be given an oral antibiotic to be taken prior to the procedure. Please follow the specific instructions from your urologist. If you have taken any antibiotics within the last 6 months, especially Cipro or Levaquin, please notify your doctor before the biopsy.
  • Purchase one (1) Fleet enema at your local pharmacy. This should be used the night before or the morning of your biopsy.
  • Drink plenty of fluids prior to the procedure.
  • You may eat on the day of the procedure. We recommend light meals. If you are diabetic, follow your usual diet and intake.

If you have any questions or concerns about the procedure or prep instructions, please contact the office.